This potato trial in India showed that Vitazyme greatly increased total tuber yield, by 8% for the in-furrow applications and by 12% for the seed application. Both Vitazyme treatments increased the percentage of largest (>45 mm) tubers above the control treatment. Income was increased as well for both Vitazyme treatments above the control, by 7% for the in-furrow treatment and by 12% for the seed treatment. Cost-benefit ratios for these two regimes were highly attractive: 3.5 for in-furrow application and 5.8 for the seed application. Clearly, Vitazyme is a highly effective management tool for improving potato tuber yield and size, and raising profitability in India.